Labetalol is a medication used to treat high blood pressure. It can be administered intravenously in severe hypertension or orally for long term hypertension management. Labetalol is a Beta- Alpha blocker, it has effects on both short and long term situations.
In short term, it decreases blood pressure by decreasing systemic vascular resistance with no increase in stroke volume.
In long term, it reduces the heart rate during exercise while maintaining cardiac output by an increase in stroke value.
Labetalol is available both in tablets at 100mg, 200mg, 300mg by different trade names, and injection at 50mg.
Mode of administration
It can be administered both intravenously and orally.
Labetalol should be given slowly
In hypertensive emergency cases, the initial dose which is usually 20mg should be given over 2 minutes
Side effects of labetalol
- Dizziness
- Tingling scalp or skin
- Headache
- Stuffy nose
- Upset stomach
- Difficult breathing
- Signs or hear problems, (fast heartbeat, chest tightness)
Contradictions
- Severe hypotension
- Any obstructive airway disease, including asthma
Nurses Responsibility in the administration of labetalol
Before administration
- Check the drug and dosage
- Check for allergies
- Check vital signs
- Explain procedure to the patient. Patient must give you consent as a nurse.
After administration
- Monitor patient for side effects. Patient is likely to sleep after administration, or complain of headache.
- Check vital signs. In case of side effects like chest tightness, rapid pulse rate.
- Psychologically reassure patient if side effects persist for longer hours
I hope this helps?
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